SCYGR8

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SCYGR8 RNA expression is significantly associated with the protein abundance of many other proteins, with 216 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SCYGR8-associated proteins across cancer lineages are RUNX3_S17, SCAPER_S185, and SEC31A_S532. Each is linked with SCYGR8 in more than 1 cancer types. Because this analysis shows association rather than direction, both SCYGR8-to-partner and partner-to-SCYGR8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SCYGR8 versus RUNX3_S17 in UCEC, with a Pearson correlation of -0.22.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SCYGR8→partner) and Y-score (partner→SCYGR8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECRUNX3_S17 →-0.411-0.092.003.00831
UCECSCAPER_S185 →+0.758+0.126<.001.00631
UCECSEC31A_S532 →-0.636-0.100.004.00531
UCECSRP72_S630 →+0.649+0.180<.001.00631
UCECTCF12_S79 →-0.285-0.079.006.00931
UCECTRIM28_S258 →+0.813+0.154<.001.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 216 associations by consensus.

SCYGR8 vs RUNX3_S17 — UCEC

Per-sample scatter of SCYGR8 vs RUNX3_S17 in UCEC (Pearson r = -0.22).

Explore this scatter interactively →

Exploration