SCYGR4

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SCYGR4 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,607 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SCYGR4-associated proteins across cancer lineages are PIP4K2A, COLEC12, and CYP1B1. Each is linked with SCYGR4 in more than 2 cancer types. Because this analysis shows association rather than direction, both SCYGR4-to-partner and partner-to-SCYGR4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SCYGR4 versus PIP4K2A in GBM, with a Pearson correlation of 0.33.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SCYGR4→partner) and Y-score (partner→SCYGR4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMPIP4K2A →+0.503+0.255<.001.00133
OVCOLEC12 →+0.732+0.153<.001<.00133
OVCYP1B1 →+0.862+0.159<.001<.00133
GBMITGAL →+0.534+0.406<.001<.00133
GBMAPBB1IP →+0.492+0.299.003.00133
GBMTARDBP →-0.401-0.272.001.00733
Each partner links to its Q-omics profile. Showing the 6 strongest of 7,607 associations by consensus.

SCYGR4 vs PIP4K2A — GBM

Per-sample scatter of SCYGR4 vs PIP4K2A in GBM (Pearson r = 0.33).

Explore this scatter interactively →

Exploration