SCYGR4

Across TCGA cell cohorts, SCYGR4 RNA expression is significantly associated with the go_rna of many other GO terms, with 220 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SCYGR4-associated GO terms across cancer lineages are Energy derivation by oxidation of organic compounds, Negative regulation of post-translational protein modification, and Regulation of macrophage colony-stimulating factor signaling pathway. Each is linked with SCYGR4 in more than 2 cancer types. Because this analysis shows association rather than direction, both SCYGR4-to-partner and partner-to-SCYGR4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Energy derivation by oxidation of organic compounds grouped by SCYGR4-low versus SCYGR4-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SCYGR4→partner) and Y-score (partner→SCYGR4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Energy derivation by oxidation of organic compounds →	+0.038	+0.024	.001	.009	3	3
LARGE_INTESTINE	Negative regulation of post-translational protein modification →	+0.040	+0.019	.002	.002	3	2
LARGE_INTESTINE	Regulation of macrophage colony-stimulating factor signaling pathway →	-0.188	-0.017	<.001	.005	3	2
LARGE_INTESTINE	Regulation of protein localization to early endosome →	+0.093	+0.019	.004	.002	3	2
LARGE_INTESTINE	Positive regulation of protein localization to early endosome →	+0.093	+0.019	.004	.002	3	2
LARGE_INTESTINE	Regulation of neurofibrillary tangle assembly →	+0.078	+0.019	.008	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 220 associations by consensus.

Energy derivation by oxidation of organic compounds by SCYGR4 expression — LARGE_INTESTINE

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