SCYGR10

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, SCYGR10 RNA expression is significantly associated with the go_rna of many other GO terms, with 203 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SCYGR10-associated GO terms across cancer lineages are Response to histamine, Regulation of PERK-mediated unfolded protein response, and Negative regulation of PERK-mediated unfolded protein response. Each is linked with SCYGR10 in more than 2 cancer types. Because this analysis shows association rather than direction, both SCYGR10-to-partner and partner-to-SCYGR10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to histamine grouped by SCYGR10-low versus SCYGR10-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SCYGR10→partner) and Y-score (partner→SCYGR10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKINResponse to histamine →-0.215-0.067.009.00833
LUNG_NSCLC_LUADRegulation of PERK-mediated unfolded protein response →+0.086+0.115.001.00333
LUNG_NSCLC_LUADNegative regulation of PERK-mediated unfolded protein response →+0.080+0.072.001.00433
LUNG_NSCLC_LUADT-helper 1 cell activation →+0.137+0.093<.001.00133
LARGE_INTESTINERegulation of synaptic membrane adhesion →-0.836-0.066.005.00233
SKINRegulation of endocytosis →+0.038+0.069.004.00632
Each partner links to its Q-omics profile. Showing the 6 strongest of 203 associations by consensus.

Response to histamine by SCYGR10 expression — SKIN

Box plot of Response to histamine in SCYGR10-low vs SCYGR10-high samples in SKIN.

Explore this box plot interactively →

Exploration