SCYGR1

Across TCGA cell cohorts, SCYGR1 RNA expression is significantly associated with the mutation status of many other genes, with 62 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible SCYGR1-associated genes across cancer lineages are GJA8, GZMH, and USP31. Each is linked with SCYGR1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SCYGR1-to-partner and partner-to-SCYGR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GJA8 grouped by SCYGR1-low versus SCYGR1-high in LARGE_INTESTINE.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SCYGR1→partner) and Y-score (partner→SCYGR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	GJA8 →	+4.022	+0.111	.006	<.001	3	2
BLOOD_Lymphoma	GZMH →	+4.867	+0.534	.009	<.001	3	1
BLOOD_Lymphoma	USP31 →	+4.867	+0.596	.009	<.001	3	1
BLOOD_Lymphoma	SIGLEC5 →	+4.867	+0.354	.009	<.001	3	1
BLOOD_Lymphoma	ELL →	+4.867	+0.579	.009	<.001	3	1
BLOOD_Lymphoma	MCM9 →	+4.867	+0.596	.009	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 62 associations by consensus.

GJA8 by SCYGR1 expression — LARGE_INTESTINE

Explore this box plot interactively →