SCTR

Across TCGA cell cohorts, SCTR RNA expression is significantly associated with the go_rna of many other GO terms, with 934 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible SCTR-associated GO terms across cancer lineages are Aerobic respiration, ATP synthesis coupled electron transport, and Mitochondrial ATP synthesis coupled electron transport. Each is linked with SCTR in more than 6 cancer types. Because this analysis shows association rather than direction, both SCTR-to-partner and partner-to-SCTR results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Aerobic respiration grouped by SCTR-low versus SCTR-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SCTR→partner) and Y-score (partner→SCTR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Aerobic respiration →	+0.052	+0.137	<.001	.003	3	7
LUNG_NSCLC_LUAD	ATP synthesis coupled electron transport →	+0.059	+0.102	.001	.006	3	7
LUNG_NSCLC_LUAD	Mitochondrial ATP synthesis coupled electron transport →	+0.059	+0.102	.001	.006	3	7
UPPER_AERODIGESTIVE_TRACT	Intracellular protein transmembrane transport →	+0.069	+0.055	<.001	.008	3	6
UPPER_AERODIGESTIVE_TRACT	Ribonucleoside triphosphate biosynthetic process →	+0.052	+0.066	.006	.004	3	6
LUNG_NSCLC_LUAD	Aerobic electron transport chain →	+0.059	+0.150	.001	.003	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 934 associations by consensus.

Aerobic respiration by SCTR expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →