SCTR-AS1

Across TCGA pan-cancer cohorts, SCTR-AS1 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated SCTR-AS1 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher SCTR-AS1 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated SCTR-AS1 expression acts as an unfavorable survival marker, although some lineages such as KIRC and SKCM show a favorable association.

KIRC, SKCM, and STAD are the cancer types where SCTR-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Tertile	IV	0.455	0.159	<.001	101	view →
SKCM	DFS	Tertile	All	0.903	0.704	.001	42	view →
STAD	DFS	Tertile	All	0.234	0.447	.002	33	view →
BRCA	DFS	Median	IV	0.367	0.773	.004	22	view →
LAML	DFS	Tertile	All	0.177	0.498	.017	18	view →
LUSC	DFS	Median	II,III,IV	0.622	0.784	.006	18	view →
PAAD	DFS	Tertile	II,III,IV	0.376	0.566	.030	16	view →
CHOL	DFS	Tertile	All	0.798	0.131	.004	14	view →
READ	OS	Quartile	IV	0.917	0.468	.031	11	view →
OV	OS	Tertile	IV	0.492	0.252	.022	8	view →
TGCT	DFS	Tertile	All	0.496	0.789	.006	8	view →
LIHC	DFS	Quartile	All	0.192	0.348	.014	7	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

SCTR-AS1–KIRC (DFS)

Open the KIRC breakdown →