SCT

Across TCGA patient cohorts, SCT RNA expression is significantly associated with the protein abundance of many other proteins, with 11,462 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible SCT-associated proteins across cancer lineages are VCAN, TAGLN, and PALLD. Each is linked with SCT in more than 6 cancer types. Because this analysis shows association rather than direction, both SCT-to-partner and partner-to-SCT results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SCT versus VCAN in OV, with a Pearson correlation of 0.75.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SCT→partner) and Y-score (partner→SCT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	VCAN →	+1.396	+1.514	<.001	<.001	3	7
OV	TAGLN →	+1.153	+1.301	<.001	<.001	3	7
OV	PALLD →	+0.936	+1.330	<.001	<.001	3	7
OV	PCOLCE →	+0.674	+1.305	<.001	<.001	3	7
HNSC	PDLIM3 →	+1.044	+1.018	<.001	<.001	3	7
COAD	PDLIM4 →	+0.610	+0.912	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,462 associations by consensus.

SCT vs VCAN — OV

Explore this scatter interactively →