Across TCGA patient cohorts, SCRT2 mutation is significantly associated with the total protein of many other genes, with 26 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SCRT2-associated genes across cancer lineages are eEF2, A-Raf_pS299, and ERK2. Each is linked with SCRT2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SCRT2-to-partner and partner-to-SCRT2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SCRT2→partner) and Y-score (partner→SCRT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eEF2 →	+0.329	+2.999	.041	.035	3	1
UCEC	A-Raf_pS299 →	-0.106	-3.000	.049	.036	3	1
UCEC	ERK2 →	+0.201	+2.700	.020	.006	3	1
UCEC	FOXO3a_pS318_S321 →	-0.179	-2.459	.001	.018	3	1
UCEC	Heregulin →	-0.144	-2.000	.009	.032	3	1
UCEC	JNK_pT183_Y185 →	-0.211	-2.687	.005	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 26 associations by consensus.

Exploration

SCRT2 survival (RNA) · tumor vs normal (RNA) · all SCRT2 data types