SCRT1

Across TCGA cell cohorts, SCRT1 mutation is significantly associated with the RNA expression of many other genes, with 14 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SCRT1-associated genes across cancer lineages are KIR2DS4, CD300H, and SULT6B1. Each is linked with SCRT1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SCRT1-to-partner and partner-to-SCRT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KIR2DS4 grouped by SCRT1-low versus SCRT1-high in STOMACH.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SCRT1→partner) and Y-score (partner→SCRT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	KIR2DS4 →	+0.050	+5.285	<.001	.003	3	1
LARGE_INTESTINE	CD300H →	+0.039	+4.415	<.001	.007	3	1
BREAST	SULT6B1 →	+0.012	+5.169	<.001	.005	3	1
BLOOD_Leukemia	C20orf85 →	+0.036	+4.969	<.001	.003	3	1
BLOOD_Leukemia	IL22 →	+0.037	+5.569	<.001	.001	3	1
BLOOD_Leukemia	ASZ1 →	+0.132	+4.152	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

KIR2DS4 by SCRT1 expression — STOMACH

Explore this box plot interactively →