SCRN2

Across TCGA cell cohorts, SCRN2 mutation is significantly associated with the drug of many other genes, with 13 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SCRN2-associated genes across cancer lineages are GSK2276186C, GSK2110183B, and Vincristine. Each is linked with SCRN2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SCRN2-to-partner and partner-to-SCRN2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GSK2276186C grouped by SCRN2-low versus SCRN2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SCRN2→partner) and Y-score (partner→SCRN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	GSK2276186C →	+0.561	+2.649	.014	.046	3	1
LARGE_INTESTINE	GSK2110183B →	+0.647	+2.649	.033	.046	3	1
LARGE_INTESTINE	Vincristine →	+0.894	+2.649	.039	.046	3	1
LARGE_INTESTINE	123829 →	+0.739	+2.649	.010	.046	3	1
LARGE_INTESTINE	GW-2580 →	+0.357	+2.786	.004	.037	3	1
LARGE_INTESTINE	50869 →	+0.585	+2.678	.004	.037	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

GSK2276186C by SCRN2 expression — LARGE_INTESTINE

Explore this box plot interactively →