SCRN1

Across TCGA pan-cancer cohorts, SCRN1 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated SCRN1 data layer compared with 25 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher SCRN1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated SCRN1 expression acts as an unfavorable survival marker, although some lineages such as GBM and HNSC show a favorable association.

CCRCC, GBM, and HNSC are the cancer types where SCRN1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Median	III,IV	0.399	0.932	.022	18	view →
GBM	OS	Median	All	0.657	0.414	.006	8	view →
HNSC	DFS	Quartile	III,IV	0.931	0.706	.025	3	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

SCRN1–CCRCC (DFS)

Open the CCRCC breakdown →