SCPEP1

Across TCGA pan-cancer cohorts, SCPEP1 mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated SCPEP1 data layer compared with 25 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher SCPEP1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated SCPEP1 expression acts as an unfavorable survival marker, although some lineages such as LSCC and CCRCC show a favorable association.

COAD, PDAC, and GBM are the cancer types where SCPEP1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	II,III,IV	0.879	1.000	.019	30	view →
PDAC	OS	Median	IV	0.381	0.951	.006	9	view →
GBM	OS	Quartile	All	0.728	0.940	.009	6	view →
OV	DFS	Median	All	0.704	1.000	.037	4	view →
LSCC	DFS	Quartile	III,IV	0.867	0.364	.019	3	view →
CCRCC	OS	Median	IV	1.000	0.451	.016	1	view →
LUAD	DFS	Median	All	0.880	0.528	.019	1	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

SCPEP1–COAD (DFS)

Open the COAD breakdown →