SCPEP1

Across TCGA patient cohorts, SCPEP1 protein abundance is significantly associated with the RNA expression of many other genes, with 13,792 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SCPEP1-associated genes across cancer lineages are GPNMB, NPL, and PARVG. Each is linked with SCPEP1 in more than 6 cancer types. Because this analysis shows association rather than direction, both SCPEP1-to-partner and partner-to-SCPEP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SCPEP1 versus GPNMB in GBM, with a Pearson correlation of 0.59.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SCPEP1→partner) and Y-score (partner→SCPEP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	GPNMB →	+1.316	+0.498	<.001	<.001	3	7
CCRCC	NPL →	+0.633	+0.237	<.001	<.001	3	5
GBM	PARVG →	+1.003	+0.617	<.001	<.001	3	5
LSCC	AIM2 →	+1.038	+0.281	<.001	.006	3	5
GBM	TMEM52B →	+0.780	+0.450	<.001	<.001	3	5
GBM	CLEC7A →	+0.974	+0.601	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,792 associations by consensus.

SCPEP1 vs GPNMB — GBM

Explore this scatter interactively →