SCPEP1

Across TCGA cell cohorts, SCPEP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,703 significant associations in total. BONE shows the largest number of these associations.

The most reproducible SCPEP1-associated GO terms across cancer lineages are Lysosomal lumen acidification, Negative regulation of respiratory burst involved in inflammatory response, and Negative regulation of respiratory burst. Each is linked with SCPEP1 in more than 12 cancer types. Because this analysis shows association rather than direction, both SCPEP1-to-partner and partner-to-SCPEP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Lysosomal lumen acidification grouped by SCPEP1-low versus SCPEP1-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SCPEP1→partner) and Y-score (partner→SCPEP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Lysosomal lumen acidification →	+0.089	+1.089	.001	<.001	3	13
CNS	Negative regulation of respiratory burst involved in inflammatory response →	+0.095	+1.333	<.001	<.001	3	12
CNS	Negative regulation of respiratory burst →	+0.095	+1.333	<.001	<.001	3	12
SOFT_TISSUE	Response to unfolded protein →	+0.092	+1.405	<.001	<.001	3	10
URINARY_TRACT	Positive regulation of translational initiation →	+0.093	+1.433	.004	.001	2	10
CNS	Vacuolar acidification →	+0.098	+0.972	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,703 associations by consensus.

Lysosomal lumen acidification by SCPEP1 expression — SOFT_TISSUE

Explore this box plot interactively →