SCP2D1

Across TCGA pan-cancer cohorts, SCP2D1 Mutation is linked to patient survival in 7 of 34 cancer types, making it a survival-associated SCP2D1 data layer compared with 10 for mass-spec protein and 2 for mass-spec protein.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher SCP2D1 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated SCP2D1 expression acts as an unfavorable survival marker, although some lineages such as SKCM show a favorable association.

LUAD, LUSC, and LIHC are the cancer types where SCP2D1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Median	All	0.315	0.837	<.001	24	view →
LUSC	OS	Median	III,IV	0.112	0.664	.003	12	view →
LIHC	OS	Median	All	0.015	0.784	<.001	12	view →
SARC	DFS	Median	All	0.121	0.611	.041	6	view →
LGG	OS	Median	All	0.659	0.908	.009	4	view →
SKCM	DFS	Median	II,III,IV	0.926	0.668	.036	4	view →
HNSC	OS	Median	All	0.212	0.602	.033	3	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

SCP2D1–LUAD (OS)

Open the LUAD breakdown →