SCP2

Across TCGA pan-cancer cohorts, SCP2 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated SCP2 data layer compared with 23 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher SCP2 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated SCP2 expression acts as an unfavorable survival marker, although some lineages such as COAD and CCRCC show a favorable association.

COAD, CCRCC, and GBM are the cancer types where SCP2 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	II,III,IV	1.000	0.883	.023	36	view →
CCRCC	DFS	Tertile	II,III,IV	0.928	0.105	.006	25	view →
GBM	OS	Quartile	All	0.260	0.625	.005	17	view →
UCEC	OS	Quartile	All	1.000	0.825	.038	8	view →
HNSC	DFS	Median	III,IV	0.903	1.000	.004	7	view →
PDAC	DFS	Median	All	0.430	0.244	.030	4	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

SCP2–COAD (DFS)

Open the COAD breakdown →