SCOC

Across TCGA patient cohorts, SCOC RNA expression is significantly associated with the protein abundance of many other proteins, with 9,347 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible SCOC-associated proteins across cancer lineages are ARFIP1, ARHGEF6_S225, and NAGK. Each is linked with SCOC in more than 4 cancer types. Because this analysis shows association rather than direction, both SCOC-to-partner and partner-to-SCOC results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SCOC versus ARFIP1 in BRCA, with a Pearson correlation of 0.52.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SCOC→partner) and Y-score (partner→SCOC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ARFIP1 →	+0.283	+0.552	<.001	<.001	3	5
UCEC	ARHGEF6_S225 →	-0.464	-0.409	.003	.004	3	4
UCEC	NAGK →	-0.268	-0.464	<.001	<.001	3	4
LUAD	SEMA4A →	-0.419	-0.561	<.001	<.001	3	4
BRCA	KRT8 →	+0.709	+0.492	<.001	<.001	2	5
BRCA	THEMIS2 →	-0.358	-0.434	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,347 associations by consensus.

SCOC vs ARFIP1 — BRCA

Explore this scatter interactively →