SCO2

Across TCGA cell cohorts, SCO2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,034 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible SCO2-associated GO terms across cancer lineages are Mitochondrial ribosome assembly, Ribosome assembly, and Ribosomal large subunit assembly. Each is linked with SCO2 in more than 12 cancer types. Because this analysis shows association rather than direction, both SCO2-to-partner and partner-to-SCO2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial ribosome assembly grouped by SCO2-low versus SCO2-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SCO2→partner) and Y-score (partner→SCO2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Mitochondrial ribosome assembly →	+0.095	+1.067	.002	.009	3	13
URINARY_TRACT	Ribosome assembly →	+0.085	+0.904	<.001	<.001	3	11
BLOOD_Lymphoma	Ribosomal large subunit assembly →	+0.087	+0.531	<.001	<.001	3	10
LARGE_INTESTINE	RNA folding →	+0.119	+0.802	<.001	.001	2	10
SKIN	GDP-mannose biosynthetic process →	+0.111	+0.790	<.001	<.001	3	8
OESOPHAGUS	Mitochondrial large ribosomal subunit assembly →	+0.139	+1.095	.009	.009	2	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,034 associations by consensus.

Mitochondrial ribosome assembly by SCO2 expression — OESOPHAGUS

Explore this box plot interactively →