SCO1

Across TCGA patient cohorts, SCO1 protein abundance is significantly associated with the RNA expression of many other genes, with 8,653 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible SCO1-associated genes across cancer lineages are GLOD4, C1QBP, and EMP3. Each is linked with SCO1 in more than 5 cancer types. Because this analysis shows association rather than direction, both SCO1-to-partner and partner-to-SCO1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SCO1 versus GLOD4 in OV, with a Pearson correlation of 0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SCO1→partner) and Y-score (partner→SCO1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	GLOD4 →	+0.481	+0.406	<.001	<.001	3	6
LSCC	C1QBP →	+0.617	+0.271	<.001	<.001	3	5
UCEC	EMP3 →	-0.815	-0.443	<.001	<.001	3	5
UCEC	MIR222HG →	-1.117	-0.325	<.001	.005	3	5
BRCA	CCL22 →	-0.980	-0.385	.003	<.001	3	4
OV	PCDH12 →	-0.477	-0.291	.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,653 associations by consensus.

SCO1 vs GLOD4 — OV

Explore this scatter interactively →