SCO1

Across TCGA cell cohorts, SCO1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,248 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SCO1-associated GO terms across cancer lineages are RNA folding, Mitochondrial ribosome assembly, and rRNA metabolic process. Each is linked with SCO1 in more than 14 cancer types. Because this analysis shows association rather than direction, both SCO1-to-partner and partner-to-SCO1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA folding grouped by SCO1-low versus SCO1-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SCO1→partner) and Y-score (partner→SCO1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	RNA folding →	+0.146	+0.989	<.001	<.001	3	15
BLOOD_Myeloma	Mitochondrial ribosome assembly →	+0.079	+0.881	<.001	<.001	3	15
OVARY	rRNA metabolic process →	+0.095	+0.934	<.001	<.001	3	14
OVARY	Regulation of G1 to G0 transition →	+0.186	+0.934	<.001	<.001	3	14
BLOOD_Myeloma	Ribosomal large subunit assembly →	+0.130	+1.070	<.001	<.001	3	14
BLOOD_Myeloma	Ribosome assembly →	+0.094	+0.890	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,248 associations by consensus.

RNA folding by SCO1 expression — LARGE_INTESTINE

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