SCNM1

Across TCGA patient cohorts, SCNM1 mutation is significantly associated with the RNA expression of many other genes, with 402 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SCNM1-associated genes across cancer lineages are TRAJ48, RPS23P5, and NCOA4P1. Each is linked with SCNM1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SCNM1-to-partner and partner-to-SCNM1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TRAJ48 grouped by SCNM1-low versus SCNM1-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SCNM1→partner) and Y-score (partner→SCNM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	TRAJ48 →	+0.961	+4.181	.007	.009	3	2
LUAD	RPS23P5 →	+0.115	+4.481	<.001	.009	3	2
UCEC	NCOA4P1 →	+0.090	+2.239	<.001	.004	3	2
SKCM	OR5H5P →	+0.034	+7.816	<.001	.008	3	1
COAD	UBE2V1P8 →	+0.285	+6.734	<.001	<.001	3	1
COAD	RN7SL756P →	+0.568	+5.037	.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 402 associations by consensus.

TRAJ48 by SCNM1 expression — COAD

Explore this box plot interactively →