SCNM1

Across TCGA cell cohorts, SCNM1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,687 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible SCNM1-associated GO terms across cancer lineages are Spliceosome conformational change to release U4 (or U4atac) and U1 (or U11), Threonyl-tRNA aminoacylation, and Spliceosomal conformational changes to generate catalytic conformation. Each is linked with SCNM1 in more than 16 cancer types. Because this analysis shows association rather than direction, both SCNM1-to-partner and partner-to-SCNM1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Spliceosome conformational change to release U4 (or U4atac) and U1 (or U11) grouped by SCNM1-low versus SCNM1-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SCNM1→partner) and Y-score (partner→SCNM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Spliceosome conformational change to release U4 (or U4atac) and U1 (or U11) →	+0.135	+0.795	<.001	<.001	3	17
BLOOD_Myeloma	Threonyl-tRNA aminoacylation →	+0.162	+1.406	<.001	<.001	3	13
OVARY	Spliceosomal conformational changes to generate catalytic conformation →	+0.094	+0.881	<.001	<.001	2	12
STOMACH	Positive regulation of ATP-dependent activity →	+0.138	+0.984	<.001	<.001	3	8
STOMACH	Protein K63-linked deubiquitination →	+0.045	+0.614	.004	.001	3	8
LIVER	Alternative mRNA splicing, via spliceosome →	+0.091	+0.758	.001	.004	2	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,687 associations by consensus.

Spliceosome conformational change to release U4 (or U4atac) and U1 (or U11) by SCNM1 expression — OVARY

Explore this box plot interactively →