SCML4

Across TCGA cell cohorts, SCML4 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,312 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible SCML4-associated GO terms across cancer lineages are Skeletal myofibril assembly, Negative regulation of interleukin-17 production, and mRNA stabilization. Each is linked with SCML4 in more than 4 cancer types. Because this analysis shows association rather than direction, both SCML4-to-partner and partner-to-SCML4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Skeletal myofibril assembly grouped by SCML4-low versus SCML4-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SCML4→partner) and Y-score (partner→SCML4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Skeletal myofibril assembly →	-0.670	-1.307	<.001	.001	3	5
SKIN	Negative regulation of interleukin-17 production →	-0.180	-2.214	<.001	<.001	3	4
BLOOD_Leukemia	mRNA stabilization →	+0.034	+0.916	.002	<.001	3	4
BONE	Chondroblast differentiation →	-1.292	-0.186	<.001	.001	2	5
BONE	Endothelial cell morphogenesis →	-0.642	-0.112	.008	.003	3	4
SKIN	Blastocyst development →	-0.092	-1.743	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,312 associations by consensus.

Skeletal myofibril assembly by SCML4 expression — BLOOD_Leukemia

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