SCML4

Across TCGA cell cohorts, SCML4 protein abundance is significantly associated with the RNA expression of many other genes, with 1,354 significant associations in total. OESOPHAGUS shows the largest number of these associations.

The most reproducible SCML4-associated genes across cancer lineages are PLIN3, TADA1, and VEZF1. Each is linked with SCML4 in more than 4 cancer types. Because this analysis shows association rather than direction, both SCML4-to-partner and partner-to-SCML4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SCML4 versus PLIN3 in OESOPHAGUS, with a Pearson correlation of 0.57.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SCML4→partner) and Y-score (partner→SCML4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	PLIN3 →	+1.589	+1.255	.003	.006	3	5
OESOPHAGUS	TADA1 →	+0.796	+1.646	.007	.004	3	4
BLOOD_Leukemia	VEZF1 →	+0.592	+0.609	.006	.009	3	4
CNS	MIA3 →	+0.626	+0.958	<.001	.001	3	4
LUNG_NSCLC_LUAD	CNGA4 →	+0.161	+1.942	.008	<.001	3	3
LARGE_INTESTINE	FKBP3 →	-0.851	-1.061	.009	.006	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,354 associations by consensus.

SCML4 vs PLIN3 — OESOPHAGUS

Explore this scatter interactively →