SCMH1

Across TCGA pan-cancer cohorts, SCMH1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated SCMH1 data layer compared with 26 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher SCMH1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated SCMH1 expression acts as an unfavorable survival marker, although some lineages such as UCEC and LSCC show a favorable association.

LUAD, GBM, and HNSC are the cancer types where SCMH1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Tertile	III,IV	0.402	0.875	.013	18	view →
GBM	DFS	Tertile	All	0.706	0.920	.033	14	view →
HNSC	DFS	Quartile	II,III,IV	0.212	0.661	.038	5	view →
UCEC	OS	Median	All	0.974	0.849	.038	2	view →
LSCC	DFS	Tertile	II,III,IV	1.000	0.795	.046	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

SCMH1–LUAD (DFS)

Open the LUAD breakdown →