SCMH1

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SCMH1 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,452 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SCMH1-associated proteins across cancer lineages are WDR5, ZMYM4, and PPIH. Each is linked with SCMH1 in more than 4 cancer types. Because this analysis shows association rather than direction, both SCMH1-to-partner and partner-to-SCMH1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SCMH1 versus WDR5 in GBM, with a Pearson correlation of 0.55.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SCMH1→partner) and Y-score (partner→SCMH1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMWDR5 →+0.227+0.299<.001<.00135
GBMZMYM4 →+0.408+0.507<.001<.00135
HNSCPPIH →+0.215+0.669<.001.00135
GBMNELFA →+0.274+0.344<.001<.00135
CCRCCNRBF2 →-0.409-0.442.001.00135
LUADRPL26 →-0.570-0.334<.001<.00135
Each partner links to its Q-omics profile. Showing the 6 strongest of 12,452 associations by consensus.

SCMH1 vs WDR5 — GBM

Per-sample scatter of SCMH1 vs WDR5 in GBM (Pearson r = 0.55).

Explore this scatter interactively →

Exploration