SCMH1

Across TCGA cell cohorts, SCMH1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,524 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SCMH1-associated GO terms across cancer lineages are RISC complex assembly, Subtelomeric heterochromatin formation, and Heterochromatin organization. Each is linked with SCMH1 in more than 11 cancer types. Because this analysis shows association rather than direction, both SCMH1-to-partner and partner-to-SCMH1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RISC complex assembly grouped by SCMH1-low versus SCMH1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SCMH1→partner) and Y-score (partner→SCMH1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	RISC complex assembly →	+0.125	+0.802	<.001	.002	3	12
BLOOD_Myeloma	Subtelomeric heterochromatin formation →	+0.109	+0.715	<.001	.006	3	12
PANCREAS	Heterochromatin organization →	+0.061	+0.950	<.001	<.001	3	11
SOFT_TISSUE	Centrosome cycle →	+0.086	+0.895	<.001	<.001	3	11
LARGE_INTESTINE	DNA biosynthetic process →	+0.068	+0.755	<.001	<.001	3	11
PANCREAS	Negative regulation of gene expression, epigenetic →	+0.064	+0.899	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,524 associations by consensus.

RISC complex assembly by SCMH1 expression — BONE

Explore this box plot interactively →