SCLT1

Across TCGA patient cohorts, SCLT1 mutation is significantly associated with the RNA expression of many other genes, with 2,674 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SCLT1-associated genes across cancer lineages are RNU6-751P, TMEM104, and SLC17A5. Each is linked with SCLT1 in more than 2 cancer types. Because this analysis shows association rather than direction, both SCLT1-to-partner and partner-to-SCLT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-751P grouped by SCLT1-low versus SCLT1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SCLT1→partner) and Y-score (partner→SCLT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RNU6-751P →	+0.112	+4.640	<.001	.003	3	3
SKCM	TMEM104 →	+0.615	+3.341	.003	.005	3	2
SKCM	SLC17A5 →	+0.975	+3.328	.001	.005	3	2
KIRC	RSL24D1P4 →	+0.127	+5.199	<.001	.007	3	2
KIRC	YWHAEP4 →	+0.302	+5.316	<.001	.006	3	2
SKCM	RNU6-794P →	+0.158	+4.049	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,674 associations by consensus.

RNU6-751P by SCLT1 expression — SKCM

Explore this box plot interactively →