SCIMP

Across TCGA patient cohorts, SCIMP RNA expression is significantly associated with the protein abundance of many other proteins, with 20,616 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SCIMP-associated proteins across cancer lineages are WAS, WDFY4, and WIPF1. Each is linked with SCIMP in more than 9 cancer types. Because this analysis shows association rather than direction, both SCIMP-to-partner and partner-to-SCIMP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SCIMP versus WAS in GBM, with a Pearson correlation of 0.68.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SCIMP→partner) and Y-score (partner→SCIMP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	WAS →	+0.538	+0.633	<.001	<.001	3	10
LSCC	WDFY4 →	+0.556	+0.817	<.001	<.001	3	10
UCEC	WIPF1 →	+0.571	+0.843	<.001	<.001	3	10
GBM	PLCB2 →	+0.531	+0.625	<.001	<.001	3	10
UCEC	PLEK →	+0.868	+0.838	<.001	<.001	3	10
OV	PLEKHO2 →	+0.503	+0.903	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,616 associations by consensus.

SCIMP vs WAS — GBM

Explore this scatter interactively →