SCIMP

Across TCGA cell cohorts, SCIMP RNA expression is significantly associated with the go_rna of many other GO terms, with 3,135 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible SCIMP-associated GO terms across cancer lineages are RNA localization, Establishment of RNA localization, and Positive regulation of gene expression, epigenetic. Each is linked with SCIMP in more than 10 cancer types. Because this analysis shows association rather than direction, both SCIMP-to-partner and partner-to-SCIMP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA localization grouped by SCIMP-low versus SCIMP-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SCIMP→partner) and Y-score (partner→SCIMP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	RNA localization →	+0.112	+0.107	<.001	.001	3	11
BONE	Establishment of RNA localization →	+0.154	+0.136	<.001	<.001	3	11
LIVER	Positive regulation of gene expression, epigenetic →	+0.079	+0.064	.003	.002	3	10
OVARY	Regulation of telomere maintenance →	+0.054	+0.076	.001	.002	3	10
UPPER_AERODIGESTIVE_TRACT	mRNA splice site recognition →	+0.186	+0.130	<.001	.003	3	10
BONE	RNA export from nucleus →	+0.117	+0.089	<.001	.007	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,135 associations by consensus.

RNA localization by SCIMP expression — BONE

Explore this box plot interactively →