SCIMP

Across TCGA cell cohorts, SCIMP protein abundance is significantly associated with the RNA expression of many other genes, with 184 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible SCIMP-associated genes across cancer lineages are ANO8, VGLL1, and SIPA1L3. Each is linked with SCIMP in more than 1 cancer types. Because this analysis shows association rather than direction, both SCIMP-to-partner and partner-to-SCIMP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SCIMP versus ANO8 in SKIN, with a Pearson correlation of 0.87.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SCIMP→partner) and Y-score (partner→SCIMP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	ANO8 →	+1.035	+1.311	.001	.004	3	2
SKIN	VGLL1 →	+0.120	+1.315	.001	.002	3	1
SKIN	SIPA1L3 →	+1.255	+1.750	.009	.003	3	1
SKIN	YWHAE →	+0.419	+1.630	.009	.003	3	1
SKIN	RSRC2 →	+0.687	+1.555	.005	.001	3	1
SKIN	SUDS3 →	+0.907	+1.402	.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 184 associations by consensus.

SCIMP vs ANO8 — SKIN

Explore this scatter interactively →