SCHIP1

Across TCGA patient cohorts, SCHIP1 RNA expression is significantly associated with the protein abundance of many other proteins, with 19,665 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SCHIP1-associated proteins across cancer lineages are SEC23B, SVIL, and RAB23. Each is linked with SCHIP1 in more than 8 cancer types. Because this analysis shows association rather than direction, both SCHIP1-to-partner and partner-to-SCHIP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SCHIP1 versus SEC23B in HNSC, with a Pearson correlation of -0.30.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SCHIP1→partner) and Y-score (partner→SCHIP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	SEC23B →	-0.346	-0.526	<.001	<.001	3	9
UCEC	SVIL →	+0.487	+0.574	<.001	<.001	3	7
BRCA	RAB23 →	+0.524	+0.260	<.001	<.001	3	7
UCEC	SEPTIN11 →	+0.473	+0.637	<.001	.003	3	6
OV	SPON2 →	+1.053	+0.466	.008	.003	3	6
COAD	CCN1 →	+0.869	+0.180	.001	.002	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,665 associations by consensus.

SCHIP1 vs SEC23B — HNSC

Explore this scatter interactively →