SCGN

Across TCGA patient cohorts, SCGN RNA expression is significantly associated with the protein abundance of many other proteins, with 9,677 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible SCGN-associated proteins across cancer lineages are COLGALT1, MDM1_S601, and SORBS2. Each is linked with SCGN in more than 4 cancer types. Because this analysis shows association rather than direction, both SCGN-to-partner and partner-to-SCGN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SCGN versus COLGALT1 in BRCA, with a Pearson correlation of -0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SCGN→partner) and Y-score (partner→SCGN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	COLGALT1 →	-0.422	-1.226	.001	.005	3	5
OV	MDM1_S601 →	+0.776	+0.060	.001	.005	3	4
COAD	SORBS2 →	+0.704	+0.879	<.001	.001	3	4
CCRCC	TNS2 →	+0.518	+3.013	<.001	<.001	3	4
CCRCC	NCF1 →	-0.533	-2.363	.003	<.001	3	4
CCRCC	NCF4 →	-0.450	-2.142	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,677 associations by consensus.

SCGN vs COLGALT1 — BRCA

Explore this scatter interactively →