SCGN

Across TCGA cell cohorts, SCGN RNA expression is significantly associated with the go_rna of many other GO terms, with 2,024 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible SCGN-associated GO terms across cancer lineages are Regulation of glucan biosynthetic process, Regulation of glycogen biosynthetic process, and Folic acid transport. Each is linked with SCGN in more than 5 cancer types. Because this analysis shows association rather than direction, both SCGN-to-partner and partner-to-SCGN results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of glucan biosynthetic process grouped by SCGN-low versus SCGN-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SCGN→partner) and Y-score (partner→SCGN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Regulation of glucan biosynthetic process →	+0.075	+1.437	.001	.003	3	6
BREAST	Regulation of glycogen biosynthetic process →	+0.075	+1.437	.001	.003	3	6
SOFT_TISSUE	Folic acid transport →	+0.080	+0.097	.005	.001	3	5
SOFT_TISSUE	Negative regulation of translation →	+0.043	+0.080	.001	.003	3	5
LIVER	Xenobiotic export from cell →	+0.260	+2.806	<.001	<.001	3	5
BREAST	Glycerophospholipid metabolic process →	+0.026	+0.988	.001	.007	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,024 associations by consensus.

Regulation of glucan biosynthetic process by SCGN expression — BREAST

Explore this box plot interactively →