SCGB2B2

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SCGB2B2 mutation is significantly associated with the RNA expression of many other genes, with 464 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SCGB2B2-associated genes across cancer lineages are RNU6-847P, RN7SL191P, and RN7SL702P. Each is linked with SCGB2B2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SCGB2B2-to-partner and partner-to-SCGB2B2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SCGB2B2→partner) and Y-score (partner→SCGB2B2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCARNU6-847P →+0.242+8.055<.001.00732
UCECRN7SL191P →+0.154+3.081.004.00232
COADRN7SL702P →+0.630+5.790<.001.00332
COADVENTXP3 →+0.130+5.435<.001.00532
BRCAENPP7P13 →+0.109+8.055<.001.00731
BRCARNU6-84P →+0.252+8.471<.001.00531
Each partner links to its Q-omics profile. Showing the 6 strongest of 464 associations by consensus.

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