SCGB2A1

Across TCGA patient cohorts, SCGB2A1 mutation is significantly associated with the total protein of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SCGB2A1-associated genes across cancer lineages are Myosin-IIa and FOXO3a. Each is linked with SCGB2A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SCGB2A1-to-partner and partner-to-SCGB2A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Myosin-IIa grouped by SCGB2A1-low versus SCGB2A1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SCGB2A1→partner) and Y-score (partner→SCGB2A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Myosin-IIa →	+0.259	+2.814	.022	.036	3	1
UCEC	FOXO3a →	+0.166	+2.820	.007	.036	2	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Myosin-IIa by SCGB2A1 expression — UCEC

Explore this box plot interactively →