Across TCGA pan-cancer cohorts, SCGB1D4 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of SCGB1D4’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where SCGB1D4 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types SCGB1D4 is over-expressed in tumor, although a few such as PRAD show the opposite, repressed pattern.

BRCA, PRAD, and LUSC are the cancer types where SCGB1D4 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SCGB1D4 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	Female	II,III,IV	+0.119	.033	4	view →
PRAD	All	All	−0.488	.009	2	view →
LUSC	All	All	+0.013	.041	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: SCGB1D4 RNA expression & survival · all SCGB1D4 data types