SCGB1D1

Across TCGA patient cohorts, SCGB1D1 mutation is significantly associated with the RNA expression of many other genes, with 248 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SCGB1D1-associated genes across cancer lineages are RNA5SP411, RNA5SP396, and RNA5SP30. Each is linked with SCGB1D1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SCGB1D1-to-partner and partner-to-SCGB1D1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP411 grouped by SCGB1D1-low versus SCGB1D1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SCGB1D1→partner) and Y-score (partner→SCGB1D1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP411 →	+1.426	+2.808	<.001	<.001	3	2
UCEC	RNA5SP396 →	+0.563	+3.162	<.001	.001	3	2
UCEC	RNA5SP30 →	+0.606	+2.345	<.001	.007	3	2
UCEC	RNA5SP369 →	+0.445	+2.345	<.001	.007	3	2
UCEC	HNRNPH3P1 →	+0.100	+2.257	.002	.009	3	2
UCEC	RNA5SP410 →	+0.733	+2.374	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 248 associations by consensus.

RNA5SP411 by SCGB1D1 expression — UCEC

Explore this box plot interactively →