SCGB1D1

Across TCGA patient cohorts, SCGB1D1 mutation is significantly associated with the total protein of many other genes, with 7 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SCGB1D1-associated genes across cancer lineages are MYH11, Rictor, and Shc_pY317. Each is linked with SCGB1D1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SCGB1D1-to-partner and partner-to-SCGB1D1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MYH11 grouped by SCGB1D1-low versus SCGB1D1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SCGB1D1→partner) and Y-score (partner→SCGB1D1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MYH11 →	+1.234	+2.321	.032	.035	3	1
UCEC	Rictor →	+0.747	+3.179	.008	.010	3	1
UCEC	Shc_pY317 →	-0.213	-3.169	.005	.019	3	1
UCEC	VHL →	-1.089	-3.321	.001	.010	3	1
UCEC	XRCC1 →	-0.156	-2.321	.048	.035	2	1
UCEC	Caspase-8 →	-0.361	-3.321	.004	.010	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

MYH11 by SCGB1D1 expression — UCEC

Explore this box plot interactively →