SCGB1A1

Across TCGA pan-cancer cohorts, SCGB1A1 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated SCGB1A1 data layer compared with 24 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher SCGB1A1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated SCGB1A1 expression acts as an unfavorable survival marker.

LUAD, HNSC, and LSCC are the cancer types where SCGB1A1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Median	All	0.764	1.000	.004	14	view →
HNSC	OS	Tertile	All	0.326	1.000	.036	12	view →
LSCC	DFS	Tertile	II,III,IV	0.865	1.000	.011	6	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

SCGB1A1–LUAD (OS)

Open the LUAD breakdown →