SCGB1A1

Across TCGA patient cohorts, SCGB1A1 mutation is significantly associated with the RNA expression of many other genes, with 38 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SCGB1A1-associated genes across cancer lineages are LINC02079, YWHAQP7, and RN7SKP27. Each is linked with SCGB1A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SCGB1A1-to-partner and partner-to-SCGB1A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC02079 grouped by SCGB1A1-low versus SCGB1A1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SCGB1A1→partner) and Y-score (partner→SCGB1A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	LINC02079 →	+0.284	+5.226	<.001	<.001	3	2
UCEC	YWHAQP7 →	+0.182	+3.892	<.001	.004	3	1
LUAD	RN7SKP27 →	+0.093	+7.930	.002	.008	3	1
LUAD	MIR3180-4 →	+0.193	+7.930	<.001	.008	3	1
LUAD	APONP →	+0.064	+7.930	<.001	.008	3	1
UCEC	SEPTIN14P19 →	+0.051	+5.245	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 38 associations by consensus.

LINC02079 by SCGB1A1 expression — UCEC

Explore this box plot interactively →