SCG5

Across TCGA patient cohorts, SCG5 protein abundance is significantly associated with the RNA expression of many other genes, with 4,914 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SCG5-associated genes across cancer lineages are SERPINI1, CHGB, and ABCG4. Each is linked with SCG5 in more than 2 cancer types. Because this analysis shows association rather than direction, both SCG5-to-partner and partner-to-SCG5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SCG5 versus SERPINI1 in BRCA, with a Pearson correlation of 0.65.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SCG5→partner) and Y-score (partner→SCG5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SERPINI1 →	+3.978	+2.012	<.001	.006	3	3
BRCA	CHGB →	+8.284	+1.884	.003	.004	3	3
GBM	ABCG4 →	+0.436	+0.460	<.001	<.001	3	2
GBM	HSD3BP3 →	+0.493	+0.603	<.001	<.001	3	2
BRCA	PRMT8 →	+1.415	+1.895	.009	.003	3	2
BRCA	TMOD2 →	+1.046	+1.300	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,914 associations by consensus.

SCG5 vs SERPINI1 — BRCA

Explore this scatter interactively →