SCG5-AS1

Across TCGA pan-cancer cohorts, SCG5-AS1 RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated SCG5-AS1 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher SCG5-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated SCG5-AS1 expression acts as an unfavorable survival marker, although some lineages such as UCS and BLCA show a favorable association.

ACC, KIRC, and KICH are the cancer types where SCG5-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	OS	Median	All	0.748	0.957	<.001	100	view →
KIRC	OS	Tertile	All	0.469	0.688	<.001	98	view →
KICH	DFS	Tertile	All	0.630	0.950	<.001	82	view →
UVM	DFS	Tertile	All	0.216	0.806	<.001	75	view →
LGG	DFS	Median	All	0.659	0.807	<.001	47	view →
LIHC	DFS	Median	III,IV	0.173	0.424	.002	32	view →
UCS	DFS	Tertile	IV	0.818	0.237	.024	24	view →
LUAD	DFS	Tertile	IV	0.200	0.632	.007	18	view →
COAD	DFS	Tertile	All	0.441	0.591	.015	16	view →
READ	DFS	Median	IV	0.179	0.936	.010	13	view →
CHOL	OS	Quartile	III,IV	0.136	0.829	.008	12	view →
LAML	DFS	Median	All	0.461	0.684	.018	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 26 lineages.

SCG5-AS1–ACC (OS)

Open the ACC breakdown →