Across TCGA patient cohorts, SCFD2 mutation is significantly associated with the RNA expression of many other genes, with 2,261 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SCFD2-associated genes across cancer lineages are RNU6-1137P, IMPDH1P11, and RNA5SP423. Each is linked with SCFD2 in more than 2 cancer types. Because this analysis shows association rather than direction, both SCFD2-to-partner and partner-to-SCFD2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SCFD2→partner) and Y-score (partner→SCFD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RNU6-1137P →	+0.155	+4.147	<.001	.009	3	3
BLCA	IMPDH1P11 →	+0.074	+3.618	<.001	.008	3	3
CESC	RNA5SP423 →	+0.449	+5.837	<.001	.001	3	3
UCEC	BNIP3 →	+0.701	+2.243	.001	.005	3	3
SKCM	HDHD5 →	+0.639	+3.478	<.001	.002	3	3
UCEC	EZH2P1 →	+0.204	+1.463	.007	.006	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,261 associations by consensus.

Exploration

SCFD2 survival (RNA) · tumor vs normal (RNA) · all SCFD2 data types