Across TCGA pan-cancer cohorts, SCDP1 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of SCDP1’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where SCDP1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types SCDP1 is over-expressed in tumor, although a few such as BRCA and CHOL show the opposite, repressed pattern.
KIRC, COAD, and UCEC are the cancer types where SCDP1 tumor–normal differential expression is most reproducible.
RNA tumor vs normal associations by lineage
Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SCDP1 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.