SCCPDH

Across TCGA patient cohorts, SCCPDH protein abundance is significantly associated with the RNA expression of many other genes, with 14,963 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible SCCPDH-associated genes across cancer lineages are PI3, FCGR3B, and FPR2. Each is linked with SCCPDH in more than 5 cancer types. Because this analysis shows association rather than direction, both SCCPDH-to-partner and partner-to-SCCPDH results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SCCPDH versus PI3 in HNSC, with a Pearson correlation of -0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SCCPDH→partner) and Y-score (partner→SCCPDH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	PI3 →	-2.418	-0.580	<.001	<.001	3	6
OV	FCGR3B →	-1.498	-0.569	<.001	<.001	3	6
COAD	FPR2 →	-1.177	-0.534	<.001	<.001	3	6
OV	LILRB3 →	-0.812	-0.526	<.001	<.001	3	6
BRCA	COG2 →	+0.492	+0.463	<.001	<.001	3	6
HNSC	KIF28P →	+0.844	+0.919	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,963 associations by consensus.

SCCPDH vs PI3 — HNSC

Explore this scatter interactively →