SCARNA5

Across TCGA pan-cancer cohorts, SCARNA5 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated SCARNA5 data layer.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher SCARNA5 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated SCARNA5 expression acts as an unfavorable survival marker, although some lineages such as LUAD and BRCA show a favorable association.

LUAD, BRCA, and ACC are the cancer types where SCARNA5 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Quartile	II,III,IV	0.805	0.584	<.001	100	view →
BRCA	OS	Median	All	0.943	0.902	<.001	58	view →
ACC	DFS	Tertile	All	0.258	0.697	.001	55	view →
STAD	DFS	Quartile	III,IV	0.671	0.324	.002	48	view →
UCS	OS	Median	III,IV	0.491	0.195	.015	42	view →
COAD	DFS	Tertile	III,IV	0.845	0.572	.003	41	view →
CESC	DFS	Quartile	III,IV	0.911	0.584	.009	32	view →
GBM	OS	Tertile	All	0.515	0.317	.003	22	view →
MESO	DFS	Quartile	All	0.937	0.256	.006	18	view →
SKCM	OS	Median	III,IV	0.618	0.273	.001	18	view →
READ	DFS	Tertile	III,IV	0.190	0.761	.012	12	view →
KIRP	DFS	Quartile	All	1.000	0.902	.007	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

SCARNA5–LUAD (DFS)

Open the LUAD breakdown →