SCARNA10

Across TCGA pan-cancer cohorts, SCARNA10 RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of SCARNA10’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where SCARNA10 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types SCARNA10 is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.

HNSC, BRCA, and STAD are the cancer types where SCARNA10 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SCARNA10 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	II,III,IV	+0.222	.004	7	view →
BRCA	Female	All	+0.468	.008	4	view →
STAD	Female	III,IV	+1.444	.008	2	view →
THCA	Male	II,III,IV	−0.646	.036	2	view →
LUSC	All	All	+0.331	.006	2	view →
COAD	All	II,III,IV	+0.294	.013	2	view →
KIRP	All	All	+0.207	.020	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 7 strongest of 7 lineages.

SCARNA10–HNSC

Open the HNSC breakdown →