SCARF2

Across TCGA cell cohorts, SCARF2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,304 significant associations in total. BONE shows the largest number of these associations.

The most reproducible SCARF2-associated GO terms across cancer lineages are Cell division, tRNA transcription, and Negative regulation of smoothened signaling pathway. Each is linked with SCARF2 in more than 12 cancer types. Because this analysis shows association rather than direction, both SCARF2-to-partner and partner-to-SCARF2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cell division grouped by SCARF2-low versus SCARF2-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SCARF2→partner) and Y-score (partner→SCARF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Cell division →	+0.092	+1.495	<.001	.004	3	13
LARGE_INTESTINE	tRNA transcription →	+0.078	+0.903	<.001	.003	3	12
STOMACH	Negative regulation of smoothened signaling pathway →	+0.079	+1.777	<.001	<.001	3	12
STOMACH	Regulation of cell cycle G1/S phase transition →	+0.076	+1.576	.001	.008	3	11
BONE	Positive regulation of actin filament bundle assembly →	+0.178	+1.526	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Positive regulation of intracellular transport →	+0.076	+1.402	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,304 associations by consensus.

Cell division by SCARF2 expression — BREAST

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